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What Are the Changes/activities That Occur in the Brain to Cause Addiction?

Question by Angi O: What are the changes/activities that occur in the brain to cause addiction?
Is anyone familiar with more specifics of what happens in the brain when someone becomes addicted to drugs?

Best answer:

Answer by teo
Down regulation, Dopamine release, the limbic system hijacks the frontal cortex and reinforces drug seeking behavior. I am AD 102 as well, guess who I am

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